-2000 Plague -1750 Biblical plague of the Philistines now has a name, Tularemia." "The biblical plague of the Philistines now has a name, tularemia." "The laboratory isolation of F. tularensis requires special media such as buffered charcoal yeast extract agar. It cannot be isolated in the routine culture media because of the need for sulfhydryl group donors (such as cysteine)." - Wiki Thus a cysteine deficiency or chronic low cysteine would be expected to make this disease worse, the bacterium gets it first, the immune systems gets what's left over. Which wasn't enough in the first place. Death follows. -1715 Rabbit Fever - Tularemia in Ancient Egypt Did an epidemic of tularemia in Ancient Egypt affect the course of world history? -1320 Were ‘cursed’ rams the first biological weapons? Rabbit Fever - Tularemia

-1075 Rabbit fever 1520 Smallpox was first introduced into the New World as early as 1520 when the Spaniards invaded Mexico and it killed "over one half of the native population 1540 Salmonella enterica epidemic in Mexico