Latent infection from an asymptotic patient.

By Donald G. McNeil Jr.
July 23, 2018


The New York Times reported on a Lancet paper which details a case whereby an asymptotic mother and baby survived where the rest of the family were infected and killed.

From the summary of the Lancet paper:
"Based on serology and epidemiological and genomic data, the most plausible scenario is that a female case in the November, 2015, cluster survived Ebola virus disease in 2014, had viral persistence or recurrent disease, and transmitted the virus to three family members a year later."

Note that this is a guess and not the only possible explanation, this is an explanation from industry, who do not have a working vaccine.

"On Nov 17, 2015, a 15-year-old boy presented to a hospital in Monrovia, Liberia, with symptoms consistent with Ebola virus infection. A blood specimen obtained from the patient tested positive on Nov 19, 2015, for the presence of Ebola virus RNA and health authorities were notified immediately of the confirmed diagnosis of Ebola virus disease"

"A non-research determination was issued by the CDC and the US Army Medical Research Institute of Infectious Diseases Office of Human Use and Ethics for this public health outbreak investigation".

"Both the 15-year-old boy (individual A) and his 8-year-old brother (individual C) received ZMapp (Mapp Biopharmaceutical, San Diego, CA, USA) as part of the Partnership for Research on Ebola Virus in Liberia (PREVAIL) medical countermeasures study by the Liberia Ministry of Health and US National Institutes of Health. Individual A died on Nov 23, 2015."


https://emu.edu/now/news/2018/biochemistry-degree-theater-involvement-liberal-arts-education-prepared-ebola-researcher-challenging-work
Biochemistry degree, theater involvement and liberal arts education prepared this Ebola researcher for challenging work

Jonathan Nofziger manages the daily operation of clinical laboratories at several locations that are part of the Partnership for Research on Ebola Virus in Liberia, which is looking at long-term health effects of EVD in survivors. In that role, Nofziger supervises laboratory technicians collecting and processing samples, operates and performs detailed troubleshooting and maintenance on laboratory equipment, and maintains computer and networking systems used in the lab.




jul-03: Latent infection from an asymptotic patient.
https://www.nytimes.com/2018/07/23/health/ebola-transmission-female-survivor.html


LiberiaLab: Biochemistry degree, theater involvement and liberal arts education prepared this Ebola researcher for challenging work
https://emu.edu/now/news/2018/biochemistry-degree-theater-involvement-liberal-arts-education-prepared-ebola-researcher-challenging-work/