Drugmaker previously reported its original vaccine is less effective against the B1351 variant
Drug manufacturer Moderna says it will begin testing a variant-specific version of its COVID-19 vaccine that would target the B1351 variant first detected in South Africa.
The company has previously reported that its original two-dose vaccine — already approved for use in Canada — appears to provide protection against the B117 variant first detected in the U.K., as well as the B1351 variant, though its own research suggests it may be less effective against the latter.
The company says it will study the B1351 variant-specific vaccine both as a potential booster to the original COVID-19 vaccine and as a standalone for people who have not yet received a vaccine at all.
It will study the outcomes of three different scenarios:
o A single shot of the B1351 variant-specific vaccine.
o A shot combining both the original vaccine and the B1351 variant-specific booster.
o A booster of the original vaccine, added to the original two-dose version.
The B1351-specific vaccine will undergo clinical trials at the National Institutes for Health in the U.S.