2010 Osterholm Flu shot less than 60% effective, most vaccines are 90% Abstract BACKGROUND: No published meta-analyses have assessed efficacy and effectiveness of licensed influenza vaccines in the USA with sensitive and highly specific diagnostic tests to confirm influenza. "pooled efficacy 59%" INTERPRETATION: Influenza vaccines can provide moderate protection against virologically confirmed influenza, but such protection is greatly reduced or absent in some seasons. 2018 Rice Study predicts 2018 flu vaccine will likely have 20 percent efficacy "The vaccine has been changed for 2018-19, but unfortunately it still contains two critical mutations that arise from the egg-based vaccine production process," said Michael Deem, Rice's John W. Cox Professor in Biochemical and Genetic Engineering and professor of physics and astronomy. "Our study found that these same mutations halved the efficacy of flu vaccines in the past two seasons, and we expect they will lower the efficacy of the next vaccine in a similar manner." 2019 AP Flu shot protection drops from 47% to 9% in 2019 - A shot that didn't even work half the time dropped to 1 in 10 by end of season. Vaccine no match against flu bug that popped up near end ATLANTA (AP) — The flu vaccine turned out to be a big disappointment again. The vaccine didn’t work against a flu bug that popped up halfway through the past flu season, dragging down overall effectiveness to 29%, the U.S. Centers for Disease Control and Prevention reported Thursday. The flu shot was working well early in the season with effectiveness put at 47% in February. But it was virtually worthless during a second wave driven by a tougher strain, at just 9%. There was “no significant protection” against that strain, said the CDC’s Brendan Flannery. 2019 CDC Methodology 2019 NBC Vaccine no match against flu bug that popped up near end "This season's vaccine was one of the least effective in recent years." June 27, 2019, 12:11 PM EDT By Associated Press The flu vaccine turned out to be a big disappointment again. The vaccine didn't work against a flu bug that popped up halfway through the past flu season, dragging down overall effectiveness to 29 percent, the U.S. Centers for Disease Control and Prevention reported Thursday. The flu shot was working well early in the season with effectiveness put at 47 percent in February. But it was virtually worthless during a second wave driven by a tougher strain, at just 9 percent. There was "no significant protection" against that strain, said the CDC's Brendan Flannery. 2019 UMN Poor late-season protection limited flu vaccine impact for 2018-19 "The flu vaccine offered no protection against the H3N2 strain that dominated at the end of the 2018-19 US flu season, federal officials said last week, leaving overall protection from the disease at only 29%." 2019 WebMD Last Flu Season's Vaccine Only 29% Effective: CDC June 28, 2019 -- The overall effectiveness of last flu season's vaccine was only 29% because it didn't protect against a flu virus that appeared later in the season, according to the U.S. Centers for Disease Control and Prevention. It said the vaccine was 47% effective into February, but that dropped to just 9% after the late strain showed up, the Associated Press reported. avian Here is why it is a big deal that the flu shot does not work. 1) H5N1 2) Human to human transmissibility was achieved in 2017

business How vaccines became big business Tuesday, Dec. 29, 2009 Given the funding of public health agencies from the vaccine industry it's difficult to imageine they "weren't making much before flu". But that's the message here. Apparently. Canada Canada2009 WHO declares swine flu pandemic, no change in Canada's approach Canada2009Swine Swine flu roots traced to Spanish flu Canada2010dump B.C. to dump $20M in swine flu vaccine Canada2011 $425.9M pandemic flu contract awarded Canada2011who H1N1 pandemic response flawed: report Canada2012 Flu deaths reality check Canada2012Fail Flu shot linked to higher incidence of flu in pandemic year Canada2012H1N1 H1N1 flu shots likely tied to increase in paralysis syndrome Canada2012pulled Health Canada pulls distribution of Novartis flu vaccines Canada2013 "its severity is in line with the 1968 Hong Kong flu" Canada2013H1N1 "expects it will be similar to last year's 60 per cent effectiveness" Canada2014 "As well, AstraZeneca — the maker of FluMist, a vaccine puffed into a nostril — is providing 157,000 doses" Canada2014H1N1 More flu-related deaths this year than pandemic in 2009 Canada2015 Flu vaccine only 23% effective in U.S., even less effective in Canada Canada2015Fail The 2015 shot offered no protection Canada2015Paradox CBC/BC CDC - seasonal flu vaccination almost doubled the risk of infection with pandemic flu Canada2016 Flu shot effectiveness for 2015-16 disappointing, data shows Canada2016mist Flu spray fails again, U.S. panel urges shot instead Canada2017 This year's flu shot may be ineffective, but you should still get it Canada2017miscarriage Puzzling study prompts call to examine flu vaccine and miscarriage Canada2018 Last year's flu vaccine wasn't very effective. This year's looks more promising Canada2019bad Worst start to flu season since 2010 Stats Official government flu statistics chcs Practitioners are paid for each flu shot they administer See also 2017 performance figures ChildAndMom2019 "The flu shot this year also has little protection" The flu shot this year also has little protection against the strain influenza A, which has contributed to its spread and severity since mid-February. As of the past few weeks, nearly every state and U.S. territory has reported widespread flu. So far, Oregon has reached the 2016-17 flu season levels and could exceed it to be closer to last year’s uncommonly bad year. Nearly 99 percent of all people in Oregon who have gotten the flu this year have had influenza A. A Friday report from the Oregon Health Authority said that one child died from the flu the first week of March. The report for the week of Stephanie and her baby’s death has not come out yet. Oregon Health Authority officials declined to say how many children died this week. The state does not track adult flu deaths. harm 2000 Shoenfeld Vaccines role in causing autoimmune disease 2001 UNC Selenium Deficiency Causes Flu Virus To Mutate Into More Dangerous Forms 2006 Sencer In 1976 flu killed one while the flu shot killed 32 2009 Souayah Guillain-Barré syndrome after vaccination in United States 2010 Minogue System backfired. Some adult victims of severe H1N1 had lungs full of a protein called C4d (orange, left). C4d usually helps destroy viruses, but researchers think that when it met the 2009 virus, it helped kill the host instead. 2010 Monsalvo Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes 2011 Bodewes Annual Vaccination against Influenza Virus Hampers Development of Virus-Specific CD8+ T Cell Immunity in Children 2011 Lin Stroke and influenza vaccination: a case report 2012 Cowling Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine. 2012 Fail Flu shot linked to higher incidence of flu in pandemic year 2012 Soriano Giant cell arteritis and polymyalgia rheumatica after influenza vaccination 2012 Thoon Childhood Stroke after Influenza Vaccination 2013 Watanabe Influenza vaccine-induced interstitial lung disease 2015-CBC "... seasonal flu vaccination almost doubled the risk of infection with pandemic flu." 2015 CNBC Public Health Officials Know: Recently Vaccinated Individuals Spread Disease 2015 Read Immunization selects for the most pathogenic forms of a virus. 2016 Wiedermann Primary vaccine failure to routine vaccines: Why and what to do? 2017 Donahue Association of spontaneous abortion with receipt of inactivated influenza vaccine 2017 Treanor Multiply vaccinated subjects were actually more likely to develop influenza than unvaccinated subjects 2018 Arumugham "Influenza vaccines seem to be modifying influenza into a dangerous dengue-like disease" 2018 Atlantic The Perfect Storm Behind This Year's Nasty Flu Season - A strong virus, a less-than-effective vaccine, and an IV bag shortage that goes back to Hurricane Maria. 2018 Rice "The vaccine for 2018-19 contains two critical mutations that arise from the egg-based vaccine production process, these mutations halved the efficacy of flu vaccines in the past two seasons, and we expect they will lower the efficacy of the next vaccine in a similar manner." 2018 Yan vaccination was associated with higher viral shedding; vaccination with both seasonal vaccines, was associated with greater shedding 2019 RTE Settlement reached in swine flu vaccine case Elderly In 1989, only 15 percent of people over age 65 in the U.S. and Canada were vaccinated against flu. Today, more than 65 percent are immunized. Yet death rates among the elderly during flu season have increased rather than decreased. Fluvarin Contraindications and side effects Matter Does the flu shot really matter? The flu shot's dirty little secret. Nasal FluMist is a disaster Vers Inactivated influenza vaccine given alone was most commonly associated with death reports in adults (51.4%). imm More data More data about the flu shot can be found here. market Global vaccine market revenues from 2014 to 2020 The global vaccine market is showing some escalating growth and it is expected that it will reach total revenues of nearly 60 billion U.S. dollars by 2020. That would be almost double the size the market had back in 2014. Driver of the growth is the increase of various infectious diseases like influenza, swine flu, hepatitis, tuberculosis, diphtheria, Ebola, and meningococcal and pneumococcal diseases. Leading manufacturers of vaccines are big pharma companies...