In 1976 Ebola first broke out and a strange immunity to the disease was first noticed[1]. This was noticed with every infection and in 2010 the Pasteur Institute did an immunoassay of every tenth person in Gabon[2] and noticed up to 33% immunity; that is up to a third showed antibodies indicating they had had the disease but not a single person got sick or suffered any symptoms whatsoever.
Taylor[3] in 1995 proposed a hypothesis but it was Lipinski at Harvard in 2015 that published on the biochemistry of the mysterious Ebola immunity.[4] The surprise is that it works on all enveloped viruses (which is nearly all of them) yet industry ignores this and presses on with a horrendously expensive and hard to make vaccine that does not actually work. It provides some protection for "eleven days". Ebola makes you sick on the tenth day so these are misleading stats. Selenium inhibits the disulfide bond the virus must initially make with the cellular membrane of the host cell; absent this bond the virus is unable to enter and infect the cell. Inhibit that initial bond, you inhibit the virus.
The outbreaks are easy to explain. The virus is always there and never found in ares of low selenium. As long as serum selenium is high enough they're immune. The problem is logging. Nuts provide the mineral and they're valuable. It's predictable that if they remove Fika/Tiger nut trees unless there is another daily dietary source of selenium, it's only a mater of time before Ebola breaks out.
The national dish of the area is a chicken nut curry. Twice a year Fika nuts are harvested and a nut paste is made and eaten daily[5]. Ebola always breaks out right before the harvest if you notice. Fika nuts also known as Gabon nuts and the related tiger nut are the same as Brazil nuts. Two a day will optimize selenium and glutathione levels in 12 weeks[6].
[1] "The phenomenon of previously undetected, minimally symptomatic EBOV infection was evident around the discovery of the virus in 1976."
Richardson 2016 - Minimally Symptomatic Infection in an Ebola ‘Hotspot’: A Cross-Sectional Serosurvey
http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005087
[2] Becquart_2010 - High Prevalence of Both Humoral and Cellular Immunity to Zaire ebolavirus among Rural Populations in Gabon
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0009126
http://en.ird.fr/the-media-centre/scientific-newssheets/337-possible-natural-immunity-to-ebola
http://www.nytimes.com/2014/09/06/health/ebola-immunity.html
[3] Theoretical Evidence that the Ebola Virus Zaire Strain May Be Selenium-Dependent: A Factor in Pathogenesis and Viral Outbreaks?
http://orthomolecular.org/library/jom/1995/articles/1995-v10n0304-p131.shtml>http://orthomolecular.org/library/jom/1995/articles/1995-v10n0304-p131.shtml
[4] "It is known that the virulence of Ebola and other RNA enveloped viruses involves in the first step their attachment to host cell membranes. Following this initial step the virus enters the target cell cytoplasm by forming hydrophobic spikes that make holes in the membrane lipid bilayer. Formation of such spikes is catalyzed by the reduced form of viral protein disulfide isomerase (PDIred) thus initiating chain of disulfide exchange reactions. Consequently, hydrophobic protein epitopes become exposed, which in the absence of proper chaperones form hydrophobic ‘spikes’ capable of penetrating the host cell membranes.
In this communication evidence is discussed showing that the chain of disulfide exchange events can be inhibited by a small redox molecule – sodium selenite.
It is suggested that this inexpensive and readily available food supplement can be an ultimate inhibitor of Ebola and other enveloped viral infections.
http://www.journalrepository.org/media/journals/BJMMR_12/2014/Dec/Lipinski632014BJMMR14858.pdf
[5] BBC Baka - A Cry From the Rainforest
https://www.youtube.com/watch?v=8dgSWdSfFJA 11:00 27:36
The fruit has two forms (a dry season form and rainy season form) and has
many names; as a paste
the nuts last 6+ months. The word "Feka" means "fruit" in The
Jewish Neo-Aramaic Dialect of Challa.
Coula edulis: Gabon Nut, African Walnut, Congowood, Tigerwood
http://en.wikipedia.org/wiki/Coula_edulis
Irvingia gabonensis: Wild mango, African mango, bush mango, dika or ogbono
http://en.wikipedia.org/wiki/Irvingia_gabonensis
Se Foods: NIH list of Selenium containing foods
http://ods.od.nih.gov/factsheets/Selenium-HealthProfessional/
Se Nuts: Nutrients and bioactive compounds content of Baillonella toxisperma, Trichoscypha abut and Pentaclethra macrophylla from Cameroon
http://onlinelibrary.wiley.com/doi/10.1002/fsn3.217/full
close: Close but no cigar
http://anhinternational.org/2014/10/15/anh-intl-feature-musings-on-ebola-a-case-for-immune-modulation-therapy/
nsf: NSF nutrition database
http://nutritiondata.self.com/foods-000127000000000000000-w.html
recipe: Gabon: Nyembwe Chicken with Gabon Nuts
http://foodandculturerecipes.blogspot.ca/2010/10/gabon-nyembwe-chicken_752.html
[6] "Not only was consumption of two Brazil nuts each day as effective for increasing selenium status and enhancing GPx activity as 100 micrograms of selenomethionine per day, but just one Brazil nut per day would have been sufficient to raise dietary selenium intake to within recommended intake levels for the mineral."
Brazil nuts: an effective way to improve selenium status
http://ajcn.nutrition.org/content/87/2/379.full
