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March 1, 2020

Australia confirms first Covid-19 death

Australia confirmed Sunday its first death from the coronavirus amid a rise in the number of cases nationwide, Anadolu Agency reported a chief health officer as saying on Sunday.

A 78-year-old man contracted the virus known as Covid-19, while on the Diamond Princess ship in Japan and died at the Sir Charles Gairdner Hospital in Perth, according to Andrew Robertson. His wife also tested positive for the virus but is in a stable condition.

“There's no risk to the general community or staff," said Robertson.

Australia evacuated 164 of its citizens from the Diamond Princess ship in Yokohama. Nine people tested positive for the virus and were quarantined near Darwin.


Airborne transmission not primary mode for virus

The World Health Organization said current evidence has showed airborne transmission is not the primary mode for the novel coronavirus, and the principal transmission method is still thought to be respiratory droplets and close contact with an infected person.

The virus has also originated from animals, and genetic analysis shows that it may come from bats and the intermediate hosts are still unknown, according to the China-WHO COVID-19 joint survey report published on Saturday.

In China, person-to-person transmission of the virus primarily occurred between family members, it said. Of the 1,836 confirmed cases in Guangdong and Sichuan provinces found at the time of the survey, 1,308 took place in families.

Scientists from Jilin University First Hospital reported they found small traces of the novel coronavirus on the surfaces of objects in its nurse stations in quarantined areas, as well as in the air of intensive care units. The paper was published on the non-peer-reviewed preprint server medRxiv on Thursday.

While the samples that tested positive for the virus are small, only two out of 158 objects and air samples, scientists suggest that hospitals should enhance sanitation and supervision efforts to reduce the risk of patients and staff getting infected.


Two presumptive cases of Coronavirus reported in Tampa Bay, Florida, USA

Late Sunday, The Florida Department of Health announced two presumptive positive cases of COVID-19 in Florida.

One patient is an adult in Manatee County. According to the Department of Health, the patient does not have a travel history to countries identified for restricted travel by the CDC. The patient is being treated at Doctors Hospital in Sarasota.

The second patient is an adult in Hillsborough County with a history of travel to Italy. This person is isolated and will continue to remain isolated until cleared by public health officials.


Man treated in Dublin hospital as officials trace contacts

A man who had travelled from an affected area of Northern Italy was being treated in a Dublin hospital on Sunday after he was diagnosed with coronavirus on Saturday.

The man had returned from Italy and, after feeling unwell, it is understood he presented himself at a Dublin hospital where he was met by healthcare staff who were wearing hazmat type clothing.

He was taken to the isolation unit of the hospital where treatment started immediately. His condition or the severity of his symptoms are not known.

He became the first confirmed case of the virus in the Republic, following the confirmation of a occurrence of the illness in Northern Ireland earlier this week.

Public health officials are trying to trace anybody who came into contact with the man since his return from Italy. This search will initially focus on people who were in close contact with the man. This is defined as being within two metres of the man for more than 15 minutes.


https://www.malaysiakini.com/news/512769

Covid-19 in M'sia: Patient 24 infects nurse and roommate, total cases now at 29

Malaysia has recorded four new Covid-19 cases, bringing the number of recorded cases to 29.

Two of the four new cases could be traced back to the 24th case - a 41-year-old Japanese citizen working in Malaysia who had travelled to Japan.

Patient 24 had sought treatment on Feb 17 and was admitted into a private hospital on Feb 20. She was only tested positive for Covid-19 on Feb 27.

She had contributed to case 27, who is a 20-year-old trainee nurse at the private hospital.

"She (the nurse) was identified as being in close contact. n Feb 21 and 22, 2020, she had handled the case without wearing any personal protective equipment as advised.

"On Feb 27, she started to develop a cough. A screening test for Covid-19 came back positive on Feb 29," said Health Ministry director Noor Hisham Abdullah.

Patient 24 also contributed to another infection - Case 29.

Patient 29 is a 35-year-old Malaysian woman placed in the same room as Patient 24 in the private hospital on Feb 21. At the time, it was still not known that Patient 24 had Covid-19.

"On Feb 25, she (patient 29) was allowed to return home. On Feb 27, she began to feel unwell and came down with fever and cough. However, she did not seek treatment.


Ontario confirms 4 new positive cases of coronavirus, bringing provincial total to 15

Health officials have confirmed four new cases of coronavirus in Ontario, involving three men and one woman.

The men are in their 40s, 50s, and 60s, while the woman is in her 70s.

Three of the latest cases are in York Region while the other is in Toronto. The confirmation comes a day after three other positive cases were confirmed in the province, one of them also in York Region.

Dr. Karim Kurji, York Region's medical officer of health, said on Sunday that one of the patients — the man in his 40s — is the husband of the region's first patient announced on Saturday — a 34-year-old woman. The man travelled with his wife to Iran and back to Canada.

"This is related to travel to Iran," Kurji said.

"In his case, while he accompanied his wife and toddler, he didn't develop any symptoms at all until after arrival in Canada and whilst he was in isolation.


Comprehensive treatment and management of corona virus disease 2019: expert consensus statement from Shanghai Shanghai Clinical Treatment Expert Group for corona virus disease 2019

What kinds of Chinese medicinal materials have been affected by the "epidemic" during the Spring Festival?

1. Medical observation period
Clinical manifestation 1: fatigue with gastrointestinal discomfort
Recommended Chinese patent medicine: Huoxiang Zhengqi capsule (pill, water, oral liquid)

Clinical manifestation 2: fatigue with fever
Recommended Chinese patent medicine: Jinhua Qinggan granule, Lianhua Qingwen capsule (granule), Shufeng jiedu capsule (granule).


two。 Clinical treatment period (confirmed cases)

2.1 Qingfei Paidu decoction

Scope of application: suitable for mild, general, severe patients, in the treatment of critical patients can be combined with the actual situation of patients reasonable use.

Basic prescription: ephedra 9g, roasted Glycyrrhiza uralensis Fisch 6g, almond 9g, raw gypsum 15g 30g (frying first), Guizhi 9g, Zexie 9g, Polyporus umbellatus 9g, Atractylodes macrocephala 9g, Bupleurum chinense 16g, Huangling 6g, ginger Pinxia 9g, ginger 9g, Aster 9g, winter flower 9g, Seigan 9g, Asarum asparagus 6g, yam 12g, solid 6g, Chen Pei 6g, Huoxiang 9g.

Prescription: traditional Chinese medicine slices, fried in water. Pay once a day, two times in the morning and evening (40 minutes after meals), take warm clothes, pay three times a course of treatment.

If there are conditions, you can take half a bowl of rice soup at a time after taking the medicine, and you can take an extra bowl if your tongue is dry and your body fluid is deficient. (note: if the patient does not have fever, the amount of gypsum should be small, fever or strong heat can increase the amount of gypsum). If the symptoms improve but not cured, take the second course of treatment, if the patient has special circumstances or other basic diseases, the second course of treatment can be modified according to the actual situation, symptoms disappear when the drug is stopped.

Prescription source: circular of the Office of the State Administration of traditional Chinese Medicine of the General Office of the National Health and Health Commission on the recommendation of the use of "Qingfei Paidu decoction" in the treatment of pneumonia infected by novel coronavirus with integrated traditional Chinese and western medicine (letter No. 22 of the Medical Administration of the State Office of traditional Chinese Medicine (2020)).
2.2 Light weight

(1) syndrome of cold dampness and depression of lung

Clinical manifestations: fever, fatigue, soreness all over the body, cough, slight phlegm, chest tight and suffocating, dumbfounded, nausea, vomiting, stool sticky and uncomfortable. The tongue is light fat tooth mark or light red, the coating is white, thick, sapropelic or white, pulse moisturizes or slippery.

The recommended prescriptions were as follows: ephedra 6g, raw gypsum 15g, almond 9g, Qiang Huo 15g, Tingli seed 15g, Guanzhong 9g, Dilong 15g, Xu Changqing 15g, patchouli 15g, Peran 9g, Atractylodes macrocephala 15g, Yunling 45g, Atractylodes macrocephala 30g, Jiaosanxian 9g, Magnolia officinalis 15g, Jiaobetel nut 9g, simmered grass fruit 9g, ginger 15g.

Method: one dose a day, 600 ml fried in three times, one in the morning, one in the middle of the night, and taken before meals.
(2) syndrome of dampness-heat accumulation of lung

Clinical manifestations: low fever or no fever, slight cold, fatigue, heavy head and body, muscle soreness, dry expectoration, pharynx pain, dry mouth do not want to drink too much, or accompanied by chest tightness wrist ruffian, no sweat or sweat out of order, or see vomiting and malaise, loose stools or stool sticky and uncomfortable. The tongue is reddish, the moss white is thick or thin yellow, the pulse is slippery or moisturized.

The recommended prescriptions were betel nut 10g, apple 10g, Magnolia officinalis 10g, Anemarrhena asphodeloides 10 g, Huangling 10g, Bupleurum chinense 10g, Radix Paeoniae Rubra 10g, Forsythia suspensa 15g, Artemisia annua 10g, Atractylodes macrocephala 10g, Daqingye 10g and Glycyrrhiza uralensis Fisch.

Method: one dose a day, fried 400ml in two times, one time in the morning and once in the evening.
2.3 General type

(1) dampness toxin stagnation of lung syndrome

Clinical manifestations: fever, cough and phlegm, or yellow sputum, shortness of breath, abdominal distension, constipation is not smooth. The tongue is dark red, the tongue is fat, the fur is yellow, greasy or yellow dry, the pulse is slippery or the string is slippery.

The recommended prescriptions were as follows: ephedra 6g, bitter almond 15g, raw gypsum 30g, raw Coix seed 30g, Atractylodes macrocephala 10g, patchouli 15g, Artemisia artemisia 12g, Polygonum cuspidatum 20g, verbena verbena 30g, dried Reed root 30g, Tingli seed 15g, orange red 15g, raw licorice 10g.

Method: one dose a day, fried 400ml in two times, one time in the morning and once in the evening.
(2) syndrome of cold and dampness blocking lung

Clinical manifestations: low fever, warm body, or not hot, dry cough, less phlegm, burnout fatigue, chest tightness, wrist ruffian, or vomiting, loose stools. The tongue is light or reddish, the moss is white or white, and the pulse is soaked.

The recommended prescriptions were as follows: Atractylodes macrocephala 15g, tangerine peel 10g, Magnolia officinalis 10g, Huoxiang 10g, herbaceous fruit 6g, ephedra 6g, Notopterygium wilfordii 10g, ginger 10g, betel nut 10g.

Method: one dose a day, fried 400ml in two times, one time in the morning and once in the evening
2.4 heavy duty

(1) Syndrome of closed lung caused by epidemic toxin.

Clinical manifestations: febrile blush, cough, less phlegm yellow mucus, or sputum with blood, shortness of breath, fatigue and burnout, dry mouth, nausea, stool is not smooth, urination short red. The tongue is red, the coating is yellow and greasy, the pulse is slippery.

The recommended prescriptions were as follows: ephedra 6g, almond 9g, raw gypsum 15g, Glycyrrhiza uralensis Fisch 3G, Huoxiang 10g, Magnolia officinalis 10g, Atractylodes macrocephala 15g, Caoguo 10g, Pinellia ternata 9g, Poria cocos 15g, rhubarb 5g, Astragalus membranaceus 10g, Tingli 10g, Radix Paeoniae Rubra 10g.

Method: 1 ~ 2 doses per day, decoction, 100ml ≤ 200m1, 2 times a day, oral or nasal feeding.
(2) two burnt certificates of gas camp

Clinical manifestations: severe heat, thirst, shortness of breath, delirium dizziness, visual error, or macula, or vomiting, bleeding, or limb convulsions. The tongue is less moss or moss-free, and the veins are thin, or floating.

The recommended prescription was as follows: raw gypsum 30g, Anemarrhena asphodeloides 30g, place 30g, buffalo horn 30g, Radix Paeoniae Rubra 30g, Panax quinquefolium 30g, Forsythia suspensa 15g, Danpi 15g, Coptis chinensis 6g, bamboo leaf 12g, Tingli seed 15g, raw licorice 6g.

Method: 1 dose per day, water fried, first fried gypsum, buffalo horn and then all kinds of drugs, 100ml ≤ 200m1 each time, 2 times a day, oral or nasal feeding.

Recommended Chinese patent medicine: Xiyanping injection, Xuebijing injection, Reduning injection, Tanreqing injection, Xingnaojing injection. Drugs with similar efficacy can be selected according to individual conditions, or can be used in combination with clinical symptoms. Traditional Chinese medicine injection can be used in combination with traditional Chinese medicine decoction.
2.5 critical (internal and external detachment syndrome)

Clinical manifestations: dyspnea, prone to asthma or need mechanical ventilation, accompanied by dizziness, irritability, sweating limbs cold, tongue purple dark, thick or dry coating, pulse floating without root.

Recommended prescription: ginseng 15g, Heishun tablet 10g (fried first), Cornus officinalis 15g, take Suhe Xiang pills or Anguan Niuhuang pills.

Recommended Chinese patent medicine: Xuebijing injection, Redoning injection, Tanreqing injection, Xingnaojing injection, Shenfu injection, Shengmai injection, Shenmai injection. Drugs with similar efficacy can be selected according to individual conditions, or can be used in combination with clinical symptoms. Traditional Chinese medicine injection can be used in combination with traditional Chinese medicine decoction.

Note: recommended use of severe and critical traditional Chinese medicine injections

The principle that the use of traditional Chinese medicine injection should be adjusted by syndrome differentiation from low dose to step by step, the recommended usage is as follows:

Virus infection or mild bacterial infection: 0.9% sodium chloride injection 250m1 plus Xiyanping injection 100mg bid, or 0.9% sodium chloride injection 250ml heating Wenning injection 20 ml, or 0.9% sodium chloride injection 250ml plus Tanreqing injection 40ml bid.

Hyperpyrexia with disturbance of consciousness: 0.9% sodium chloride injection 250m1 plus Xingnaojing injection 20ml bid.

Systemic inflammatory response syndrome or / and multiple organ failure; 0.9% sodium oxide injection 250ml plus Xuebijing injection 100ml bid.

Immunosuppression: 0.9% sodium chloride injection 250m1 plus Shenmai injection 100m1Bir.

Shock: 0.9% sodium chloride injection 250ml plus Shenfu injection 100ml bid.
2.6 recovery period

(1) deficiency of lung and spleen qi syndrome

Clinical manifestations: shortness of breath, burnout, anorexia, anorexia, fullness, weakness of stool, loose stools. The tongue is fat and the moss is white and greasy.

Recommended prescription: Pinellia ternata 9g, Chen Pei 10g, Codonopsis pilosula 15g, roasted Huangmao 30g, fried Atractylodes macrocephala 10g, Huoling 15g, Huoxiang 10g, Amomum villosum 6g, licorice 6g.

Method: one dose a day, fried 400ml in two times, one time in the morning and once in the evening.
(2) deficiency of both qi and yin

Clinical manifestations: fatigue, shortness of breath, dry mouth, thirst, palpitation, more sweat, poor tolerance, low fever or no heat, dry cough and less phlegm. The tongue is dry and weak, and the veins are thin or weak.

The recommended prescriptions were 10 g each, 15 g of Ophiopogon officinalis, 6 g of Panax quinquefolium, 6 g of Schisandra chinensis, 15 g of raw gypsum, 10 g of light bamboo leaf, 10 g of mulberry leaf, 15 g of Reed root, 15 g of salvia miltiorrhiza and 6 g of raw Glycyrrhiza uralensis Fisch.

Method: one dose a day, fried 400ml in two times, one time in the morning and once in the evening.


TCM widely used in COVID-19 patient treatment, yielding good results

BEIJING — Traditional Chinese medicine (TCM) has been widely used to treat COVID-19 patients, yielding good outcomes, said a medical expert Feb 29.

With TCM treatment, patients with mild symptoms have seen their fever or cough alleviated, Wang Rongbing, director physician with Beijing Ditan Hospital, said at a press conference.

For severely ill patients, TCM helped relieve symptoms and restore blood oxygen saturation, preventing the patients' conditions from developing into critically ill cases, Wang said.

She also noted the effectiveness of Qingfei Paidu Soup, a herbal concoction that mixes ephedra and licorice root among other ingredients, in the treatment of COVID-19 patients with symptoms ranging from mild to critical.

Qingfei Paidu Soup has been used in 66 designated hospitals in 10 provincial-level regions, Wang said, adding that of the 1,183 patients under medical observation, 640 have been discharged from hospital and 457 have seen their symptoms eased.


https://www.bbc.com/news/uk-51697991

Thirteen more cases confirmed in UK

Twelve more people in England and one in Scotland have tested positive for coronavirus, taking the total number of UK cases to 36.

Scotland confirmed that its first patient was a Tayside resident who recently returned from Italy.

Three of the new cases in England were linked to a man from Surrey, who was the first to be infected within the UK.


U.S. bans travel to Iran, reports 1st death from COVID-19

Ontario and B.C. confirm new cases on Saturday, bringing Canada's total to 20.

The U.S. is banning travel to Iran in response to the outbreak of the new coronavirus and elevating travel warnings to regions of Italy and South Korea.

Vice-President Mike Pence announced the new restrictions and warnings as President Donald Trump said 22 people in the U.S. have been stricken by COVID-19 and that additional cases are "likely."

"We want to lower the amount of travel to and from the most impacted areas," said Alex Azar, the secretary of health and human services. "This is a basic containment strategy."

Trump provided an update on the virus after the first reported U.S. death Saturday, of a person he described as being in their late 50s and having a high medical risk.

Washington state officials issued a terse news release announcing the death. A spokesperson for EvergreenHealth Medical Center, Kayse Dahl, said the person died in the facility, but gave no details.


The virus lasts up to 9 days on surfaces.

"Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents"




aus 1: Australia confirms first Covid-19 death
http://www.malaysiakini.com/news/512753


contact: Airborne transmission not primary mode for virus
http://en.nhc.gov.cn/2020-03/01/c_77143.htm


fla 1: Two presumptive cases of Coronavirus reported in Tampa Bay, Florida, USA
https://www.abcactionnews.com/news/national/coronavirus/two-presumptive-cases-of-coronavirus-reported-in-tampa-bay


irish: Man treated in Dublin hospital as officials trace contacts
https://www.irishtimes.com/news/health/coronavirus-man-treated-in-dublin-hospital-as-officials-trace-contacts-1.4189306


msia 24: Covid-19 in M'sia: Patient 24 infects nurse and roommate, total cases now at 29
https://www.malaysiakini.com/news/512769


ontario: Ontario confirms 4 new positive cases of coronavirus, bringing provincial total to 15
https://www.cbc.ca/news/canada/toronto/new-coronavirus-cases-ontario-1.5481839


qingfei paidu: What kinds of Chinese medicinal materials have been affected by the "epidemic" during the Spring Festival?
https://www.wtdao.com/article/94/What+kinds+of+Chinese+medicinal+materials+have+been+affected+by+the+%22epidemic%22+during+the+Spring+Festival%3F.html


tcm: TCM widely used in COVID-19 patient treatment, yielding good results
http://en.nhc.gov.cn/2020-03/01/c_77149.htm


uk 36: Thirteen more cases confirmed in UK
https://www.bbc.com/news/uk-51697991


us 1: U.S. bans travel to Iran, reports 1st death from COVID-19
https://www.cbc.ca/news/world/coronavirus-covid-19-feb-29-1.5481048


kampf: The virus lasts up to 9 days on surfaces.
https://www.journalofhospitalinfection.com/article/S0195-6701(20)30046-3/fulltext