"Chemotherapy, though still primordial, must eventually provide the ultimate solution to vaccine failures. Probing the enigma of the severe influenza pandemic of 1918-1919 is an exciting contemporary venture in which genetic reconstruction of the viral genome from surviving archival RNA is being conducted with great success. ." - Hilleman, MR
Realities and enigmas of human viral influenza: pathogenesis, epidemiology and control.
https://www.ncbi.nlm.nih.gov/pubmed/12163258