rs79.vrx.palo-alto.ca.us

Private hell of Leicester scientist searching for cancer wonder drug

How salvestrol Q40 was discovered.

The Cytochrome P450 enzyme CYP1B1 only occurs in cancer cells. When certain phytoallexins such as reservetol and salvestrol are ingested these phytoallexins are converted by the P450 enzyme into picetannol, which is fatal to cancer cells but not human cells.


https://web.archive.org/web/20170609055508/https://www.sfgate.com/health/article/Prostate-cancer-drug-so-effective-trial-stopped-3603973.php

"Prostate cancer drug so effective trial stopped"

Trials of Potter's prostate drug went so well they just stopped them and gave it to everyone. - June 2, 2012

"The trial involved 1,088 men who were being treated by 151 cancer centers in 12 countries. Each was given a low dose of the steroid prednisone, which works to combat the cancer, but some received Zytiga while others were given a placebo.

All participants receiving the placebo drug were allowed in March to start taking Zytiga. Not only did they notice a slowdown in the progression of the disease, but patients also reported reduced pain and went longer before having to resort to chemotherapy.

If the FDA extends Zytiga's approval to include patients who have not yet gone through chemotherapy, more health insurers will cover the drug. The final results of the trial are expected next year."




potter: Private hell of Leicester scientist searching for cancer wonder drug
https://web.archive.org/web/20100216133946/http://www.thisisleicestershire.co.uk/news/Private-hell-Leicester-scientist-searching-cancer-wonder-drug/article-1832255-detail/article.html


trials: "Prostate cancer drug so effective trial stopped"
https://web.archive.org/web/20170609055508/https://www.sfgate.com/health/article/Prostate-cancer-drug-so-effective-trial-stopped-3603973.php