"An intraperitoneal dose of sodium ascorbate injected 10 min prior to morphine was found to provide significant protection against mortality".
"Furthermore, ascorbate may selectively attenuate specific opioid effects, i.e. respiratory depression, while having little or no action on others such as analgesia, this possibility certainly warrants further research."
EFFECT OF ASCORBATE ON THE TOXICITY OF MORPHINE IN MICE
https://www.sciencedirect.com/science/article/pii/0028390885900152